A preliminary examination of how serotonergic polymorphisms influence brain response following an adolescent cannabis intervention.
نویسندگان
چکیده
Given the link between depression, anxiety, and cannabis abuse, a serotonin receptor (rs6311) and transporter polymorphism (rs2020936) were examined as moderators of neural response as measured by functional magnetic resonance imaging following a psychosocial treatment for cannabis use disorders (CUDs). While the proposed hypotheses were unsupported, we found that the rs6311 C allele was significantly related to brain activation (medial frontal gyrus, precuneus), indicating the role of this serotonin receptor in adolescent treatment response.
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ورودعنوان ژورنال:
- Psychiatry research
دوره 204 2-3 شماره
صفحات -
تاریخ انتشار 2012